Stephanie F. L. Mott
Stephanie Mott grew up in Austria and received her M. Sc. degree in Food and Biotechnology at the University of Natural Resources and Applied Life Sciences in Vienna. Her thesis work was performed at the USDA in Beltsville, MD, titled Expression of Proteins for Therapeutical Use in Transgenic Plants. Over the course of 13 years, she gained experience working in several research labs focusing on molecular biology and clinical topics. In the Immunotherapy Laboratory of the Roger Williams Medical Center, she oversaw the growing of clinical-grade patient T cells in a GMP facility, from the pheresis of patients to the re-infusion of antibody-armed, activated T cells. At Rhode Island Hospital, she worked in the Clinical Pharmacology, the Hematology Oncology and the Liver Infectious Disease Laboratories, which are all research centers associated with the Brown University Medical School and enjoy many collaborative initiatives. While at Bryant, she has taught a number of classes including Biology, Anatoymy&Physiology, Global Health Challenges, and Biology I, Biology II and Microbiology Labs. She has also supervised several students’ semester-long research projects and advised on feasibility and optimal design of experiments. She also currently serves as the Associate Director for the Honors Program at Bryant University, as well as the Biology Coordinator.
M Sc, University of Natural Resources and Applied Life Sciences
Yang, Z. F.,Drumea, K.,Wang, J.,Rosmarin, A. G.,Mott, S., GABP transcription factor (nuclear respiratory factor 2) is required for mitochondrial biogenesis., Molecular and cellular biology, 2014.
Cheng, C. W.,Duwaerts, C. C.,Rooijen Nv, .,Wintermeyer, P.,Gregory, S. H.,Mott, S., NK cells suppress experimental cholestatic liver injury by an interleukin-6-mediated, Kupffer cell-dependent mechanism., Journal of hepatology, 2011.
Gregory, S. H.,Chen, W. H.,Palardy, J. E.,Parejo, N. A.,Heninger, S.,Anderson, C.,Artenstein, A. W.,Opal, S. M.,Cross, A. S.,Mott, S., Detoxified endotoxin vaccine (J5dLPS/OMP) protects mice against lethal respiratory challenge with Francisella tularensis SchuS4., Vaccine, 2010.
Holub, M.,Cheng, C. W.,Wintermeyer, P.,van Rooijen, N.,Gregory, S. H.,Mott, S., Neutrophils sequestered in the liver suppress the proinflammatory response of Kupffer cells to systemic bacterial infection., Journal of immunology (Baltimore, Md. : 1950), 2009.
Gregory, S. H.,Phung, J.,Lee, J.,Moise, L.,McMurry, J. A.,Martin, W.,De Groot, A. S.,Mott, S., Epitope-based vaccination against pneumonic tularemia., Vaccine, 2009.
Yang, Z. F.,Rosmarin, A. G.,Mott, S., The Ets transcription factor GABP is required for cell-cycle progression., Nature cell biology, 2007.
Chatterjee, D.,Bai, Y.,Wang, Z.,Beach, S.,Roy, R.,Braastad, C.,Sun, Y.,Mukhopadhyay, A.,Aggarwal, B. B.,Darnowski, J.,Pantazis, P.,Wyche, J.,Fu, Z.,Kitagwa, Y.,Keller, E. T.,Sedivy, J. M.,Yeung, K. C.,Mott, S., RKIP sensitizes prostate and breast cancer cells to drug-induced apoptosis., The Journal of biological chemistry, 2004.
Haidar, B.,Boucher, B.,Lee, C. Y.,Marcil, M.,Genest, Jr, J.,Mott, S., Cellular cholesterol efflux is modulated by phospholipid-derived signaling molecules in familial HDL deficiency/Tangier disease fibroblasts., Journal of lipid research, 2001.
Yu, L.,Marcil, M.,Boucher, B.,Rondeau, C.,Genest, Jr, J.,Mott, S., Decreased cellular cholesterol efflux is a common cause of familial hypoalphalipoproteinemia: role of the ABCA1 gene mutations., Atherosclerosis, 2000.
Marcil, M.,Brooks-Wilson, A.,Clee, S. M.,Roomp, K.,Zhang, L. H.,Yu, L.,Collins, J. A.,van Dam, M.,Molhuizen, H. O.,Loubster, O.,Ouellette, B. F.,Sensen, C. W.,Fichter, K.,Denis, M.,Boucher, B.,Pimstone, S.,Genest, Jr, J.,Kastelein, J. J.,Hayden, M. R.,Mott, S., Mutations in the ABC1 gene in familial HDL deficiency with defective cholesterol efflux., Lancet (London, England), 1999.
Brooks-Wilson, A.,Marcil, M.,Clee, S. M.,Zhang, L. H.,Roomp, K.,van Dam, M.,Yu, L.,Brewer, C.,Collins, J. A.,Molhuizen, H. O.,Loubser, O.,Ouelette, B. F.,Fichter, K.,Ashbourne-Excoffon, K. J.,Sensen, C. W.,Scherer, S.,Denis, M.,Martindale, D.,Frohlich, J.,Morgan, K.,Koop, B.,Pimstone, S.,Kastelein, J. J.,Genest, Jr, J.,Hayden, M. R.,Mott, S., Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency., Nature genetics, 1999.
Mott, S.,Roohani, K., Anatomy & Physiology I Lab Manual, Lab Manual for Anatomy&Physiology I Lab, 2019.
Hokeness, K.,Mott, S., Host-Pathogen Interactions: A Magnificent Battle in an Evolutionary Arms Race , National Center for Case Study Teaching in Science, 2018.
Mott, S., Microbiology Laboratory Investigations, Academx Publishing, 2016.
Mott, S. F.,Reid, A.,Langlois, G.,Hokeness, K., Biology 1 Laboratory: Principles of Biology Investigations, Academx Publishing, 2015.
Merit Award, 2022
Teaching Award, 2020
Merit Award, 2020
Merit Award, 2018
Faculty Innovation Grant, 2017
Merit Award, 2016
Biology, Anatomy&Physiology, Microbiology, Human Health
Molecular Biology, Immunology, Vaccines